EIF2B5 antibody (AA 400-450)

Catalog No. ABIN7454838

Product Details anti-EIF2B5 Antibody

Target: EIF2B5 (Eukaryotic Translation Initiation Factor 2B, Subunit 5 Epsilon, 82kDa (EIF2B5))

Binding Specificity: AA 400-450

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EIF2B5 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Purpose: Rabbit anti-eIF2B5 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: between AA 400 and 450

Isotype: IgG

Application Details

Application Notes:

IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 5 - 15 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for EIF2B5

Target: EIF2B5 (Eukaryotic Translation Initiation Factor 2B, Subunit 5 Epsilon, 82kDa (EIF2B5))

Alternative Name: eIF2B5 (EIF2B5 Products)

Synonyms: EIF2B5 antibody, F19I3.20 antibody, F19I3_20 antibody, F14P3.8 antibody, F14P3_8 antibody, AO090003000364 antibody, C81315 antibody, CACH antibody, CLE antibody, EIF-2B antibody, EIF2Bepsilon antibody, LVWM antibody, eukaryotic translation initiation factor 2B subunit epsilon antibody, eukaryotic translation initiation factor 2B, subunit 5 epsilon, 82kDa antibody, Trimeric LpxA-like enzyme antibody, translation initiation factor eif-2b epsilon subunit antibody, translation initiation factor eIF-2B epsilon subunit antibody, Translation initiation factor eIF-2B epsilon subunit, putative antibody, eukaryotic translation initiation factor 2B, subunit 5 epsilon antibody, EIF2B5 antibody, AT2G34970 antibody, AT3G02270 antibody, AOR_1_624154 antibody, CTRG_05484 antibody, PAAG_05066 antibody, CGB_A5380C antibody, TERG_01115 antibody, Eif2b5 antibody

Background: Background: eIF2B5 is one of five subunits of the eukaryotic translation initiation factor 2B (eIF2B). eIF2B5 functions as a GTP exchange factor for eukaryotic initiation factor 2 and an essential regulator for protein synthesis. Mutations in the EIF2B5 gene and the genes encoding other EIF2B subunits have been associated with leukoencephalopathy with vanishing white matter (VWM) [taken from NCBI Entrez Gene (GeneID: 8893)].

Gene ID: 8893

NCBI Accession: NP_003898

UniProt: Q13144