F11R antibody (C-Term)

Catalog No. ABIN2788778

Product Details anti-F11R Antibody

Target: F11R (F11 Receptor (F11R))

Binding Specificity: C-Term

Reactivity: Human, Cow, Dog, Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This F11R antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: AVLVTLILLG ILVFGIWFAY SRGHFDRTKK GTSSKKVIYS QPSARSEGEF

Predicted Reactivity: Cow: 85%, Dog: 92%, Human: 100%, Pig: 92%, Rabbit: 100%

Characteristics: This is a rabbit polyclonal antibody against F11R. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 299 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for F11R

Target: F11R (F11 Receptor (F11R))

Alternative Name: F11R (F11R Products)

Synonyms: CD321 antibody, JAM antibody, JAM1 antibody, JAMA antibody, JCAM antibody, KAT antibody, PAM-1 antibody, 9130004G24 antibody, AA638916 antibody, ESTM33 antibody, JAM-1 antibody, JAM-A antibody, Jcam antibody, Jcam1 antibody, Ly106 antibody, Jam1 antibody, F11 receptor antibody, F11R antibody, F11r antibody

Background: Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin superfamily gene member is an important regulator of tight junction assembly in epithelia. In addition, the encoded protein can act as (1) a receptor for reovirus, (2) a ligand for the integrin LFA1, involved in leukocyte transmigration, and (3) a platelet receptor. Multiple 5' alternatively spliced variants, encoding the same protein, have been identified but their biological validity has not been established.
Alias Symbols: CD321, JAM, JAM1, JAMA, JCAM, KAT, PAM-1
Protein Interaction Partner: SGTA, PEX19, BDNF, ELAVL1, UBC, PICK1, F11R, CGN, MPDZ, PARD3, F2RL2, TJP1, ASIP, CASK, PRKCA, PTPRB, MLLT4, ITGAL, CSNK2A1,
Protein Size: 299

Molecular Weight: 33 kDa

Gene ID: 50848

NCBI Accession: NM_016946, NP_058642

UniProt: Q9Y624

Pathways: Cell-Cell Junction Organization