F11R antibody (C-Term)

Catalog No. ABIN2788779

The Rabbit Polyclonal anti-F11R antibody (ABIN2788779) specifically detects F11R in WB. The antibody is reactive with Human, Mouse, Rat, Cow, Dog, Pig, Rabbit, Guinea Pig, Horse and Zebrafish (Danio rerio) samples.

Quick Overview for F11R antibody (C-Term) (ABIN2788779)

Target: F11R (F11 Receptor (F11R))

Reactivity: Human, Mouse, Rat, Cow, Dog, Pig, Rabbit, Guinea Pig, Horse, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This F11R antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-F11R Antibody

Binding Specificity: C-Term

Purpose: F11R Antibody - C-terminal region

Sequence: SNSSYVLNPT TGELVFDPLS ASDTGEYSCE ARNGYGTPMT SNAVRMEAVE

Predicted Reactivity: Cow: 91%, Dog: 91%, Guinea Pig: 82%, Horse: 91%, Human: 100%, Mouse: 90%, Pig: 91%, Rabbit: 91%, Rat: 100%, Zebrafish: 90%

Characteristics: This is a rabbit polyclonal antibody against F11R. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP61362-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for F11R

Target: F11R (F11 Receptor (F11R))

Alternative Name: F11R

Background:

Background Information: Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin superfamily gene member is an important regulator of tight junction assembly in epithelia. In addition, the encoded protein can act as (1) a receptor for reovirus, (2) a ligand for the integrin LFA1, involved in leukocyte transmigration, and (3) a platelet receptor. Multiple 5' alternatively spliced variants, encoding the same protein, have been identified but their biological validity has not been established.

Gene Name: F11 receptor

Alternative Symbols: JAM, KAT, JAM1, JAMA, JCAM, CD321, PAM-1

Protein Name: Junctional adhesion molecule A

Molecular Weight: 33kDa

Gene ID: 50848

NCBI Accession: NP_058642

UniProt: Q9Y624

Pathways: Cell-Cell Junction Organization