DTNA antibody (C-Term)

Catalog No. ABIN2788807

The Rabbit Polyclonal anti-DTNA antibody (ABIN2788807) specifically detects DTNA in WB. The antibody is reactive with Human, Mouse, Rat, Dog, Horse, Cow, Guinea Pig and Saccharomyces cerevisiae samples.

Quick Overview for DTNA antibody (C-Term) (ABIN2788807)

Target: DTNA (Dystrobrevin alpha (DTNA))

Reactivity: Human, Mouse, Rat, Dog, Horse, Cow, Guinea Pig, Saccharomyces cerevisiae

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DTNA antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-DTNA Antibody

Binding Specificity: C-Term

Purpose: DTNA Antibody - C-terminal region

Sequence: GATTSTMRGD MVTEDADPYV QPEDENYEND SVRQLENELQ MEEYLKQKLQ

Predicted Reactivity: Cow: 92%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 86%, Rat: 92%, Yeast: 83%

Characteristics: This is a rabbit polyclonal antibody against DTNA. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP61444-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for DTNA

Target: DTNA (Dystrobrevin alpha (DTNA))

Alternative Name: DTNA

Background:

Background Information: The protein encoded by this gene belongs to the dystrobrevin subfamily of the dystrophin family. This protein is a component of the dystrophin-associated protein complex (DPC), which consists of dystrophin and several integral and peripheral membrane proteins, including dystroglycans, sarcoglycans, syntrophins and alpha- and beta-dystrobrevin. The DPC localizes to the sarcolemma and its disruption is associated with various forms of muscular dystrophy. Mutations in this gene are associated with left ventricular noncompaction with congenital heart defects. Multiple alternatively spliced transcript variants encoding different isoforms have been identified for this gene.

Gene Name: Dystrobrevin, alpha

Alternative Symbols: DTN, DRP3, DTN-A, LVNC1, D18S892E

Protein Name: Dystrobrevin alpha Ensembl ENSP00000269192

Molecular Weight: 49kDa

Gene ID: 1837

NCBI Accession: NP_001185871

UniProt: B4DIR0