DLST antibody (C-Term)

Catalog No. ABIN2788818

This Rabbit Polyclonal antibody specifically detects DLST in WB and IHC. It exhibits reactivity toward Human, Mouse, Rat, Zebrafish (Danio rerio), Cow, Dog, Guinea Pig, Horse and Rabbit.It has been mentioned in 1 publication

Quick Overview for DLST antibody (C-Term) (ABIN2788818)

Target: DLST (Dihydrolipoamide S-Succinyltransferase (E2 Component of 2-Oxo-Glutarate Complex) (DLST))

Reactivity: Human, Mouse, Rat, Zebrafish (Danio rerio), Cow, Dog, Guinea Pig, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DLST antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-DLST Antibody

Binding Specificity: C-Term

Sequence: FADIERTITE LGEKARKNEL AIEDMDGGTF TISNGGVFGS LFGTPIINPP

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against DLST. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 453 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-DLST antibody (ABIN2788818)

Carr, Zambrano, Weidle, Goodson, Eisenach, Pyles, Courbet, King, Borst: "Protein identification using Cryo-EM and artificial intelligence guides improved sample purification." in: Journal of structural biology: X, Vol. 11, pp. 100120, (2025) (PubMed).

Target Details for DLST

Target: DLST (Dihydrolipoamide S-Succinyltransferase (E2 Component of 2-Oxo-Glutarate Complex) (DLST))

Alternative Name: DLST

Background: The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO2. It contains multiple copies of 3 enzymatic components: 2-oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3).
Alias Symbols: DLTS
Protein Interaction Partner: UBC, MRPL40, MRPL39, MRPL15, OGDH, MRPL49, ATP5B, UBD, GRK5, NDRG1, DYRK2, SIAH2, UIMC1, USP13, RUSC2, ZBTB16, ZHX1, SCFD1, ARIH2, CCDC86, PAK4, DLG5, TUBB4B, FLII, UMPS, PFN2, NAP1L1,
Protein Size: 453

Molecular Weight: 50 kDa

Gene ID: 1743

NCBI Accession: NM_001933, NP_001924

UniProt: P36957