Melatonin Receptor 1A antibody (C-Term)

Catalog No. ABIN2788825

The Rabbit Polyclonal anti-Melatonin Receptor 1A antibody is suitable to detect Melatonin Receptor 1A in samples from Human, Cow, Goat, Sheep, Dog, Guinea Pig, Horse and Rabbit. It has been validated for WB.

Quick Overview for Melatonin Receptor 1A antibody (C-Term) (ABIN2788825)

Target: Melatonin Receptor 1A (MTNR1A)

Reactivity: Human, Cow, Goat, Sheep, Dog, Guinea Pig, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Melatonin Receptor 1A antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Melatonin Receptor 1A Antibody

Binding Specificity: C-Term

Purpose: MTNR1A Antibody - C-terminal region

Sequence: GLLNQNFRKE YRRIIVSLCT ARVFFVDSSN DVADRVKWKP SPLMTNNNVV

Predicted Reactivity: Cow: 79%, Dog: 91%, Goat: 79%, Guinea Pig: 82%, Horse: 83%, Human: 100%, Rabbit: 83%, Sheep: 79%

Characteristics: This is a rabbit polyclonal antibody against MTNR1A. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP61495-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for Melatonin Receptor 1A

Target: Melatonin Receptor 1A (MTNR1A)

Alternative Name: MTNR1A

Background:

Background Information: This gene encodes one of two high affinity forms of a receptor for melatonin, the primary hormone secreted by the pineal gland. This receptor is a G-protein coupled, 7-transmembrane receptor that is responsible for melatonin effects on mammalian circadian rhythm and reproductive alterations affected by day length. The receptor is an integral membrane protein that is readily detectable and localized to two specific regions of the brain. The hypothalamic suprachiasmatic nucleus appears to be involved in circadian rhythm while the hypophysial pars tuberalis may be responsible for the reproductive effects of melatonin.

Gene Name: Melatonin receptor 1A

Alternative Symbols: MT1, MEL-1A-R

Protein Name: Melatonin receptor type 1A

Molecular Weight: 39kDa

Gene ID: 4543

NCBI Accession: NP_005949

UniProt: P48039