NVL antibody (N-Term)

Catalog No. ABIN2788850

The Rabbit Polyclonal anti-NVL antibody (ABIN2788850) specifically detects NVL in WB. The antibody is reactive with Human, Rat, Cow, Horse and Pig samples.

Quick Overview for NVL antibody (N-Term) (ABIN2788850)

Target: NVL (Nuclear VCP-Like (NVL))

Reactivity: Human, Rat, Cow, Horse, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NVL antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-NVL Antibody

Binding Specificity: N-Term

Purpose: NVL Antibody - N-terminal region

Sequence: LSCEKSNPKK PITEIQDSKD SSLLESDMKR KGKLKNKGSK RKKEDLQEVD

Predicted Reactivity: Cow: 83%, Horse: 93%, Human: 100%, Pig: 92%, Rat: 79%

Characteristics: This is a rabbit polyclonal antibody against NVL. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP61610-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for NVL

Target: NVL (Nuclear VCP-Like (NVL))

Alternative Name: NVL

Background:

Background Information: This gene encodes a member of the AAA (ATPases associated with diverse cellular activities) superfamily. Multiple transcript variants encoding different isoforms have been found for this gene. Two encoded proteins, described as major and minor isoforms, have been localized to distinct regions of the nucleus. The largest encoded protein (major isoform) has been localized to the nucleolus and shown to participate in ribosome biosynthesis (PMID: 15469983, 16782053), while the minor isoform has been localized to the nucleoplasmin.

Gene Name: Nuclear VCP-like

Alternative Symbols: NVL2

Protein Name: Nuclear valosin-containing protein-like

Molecular Weight: 83kDa

Gene ID: 4931

NCBI Accession: NP_996671

UniProt: O15381