Dematin antibody (Middle Region)
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- Target See all Dematin (EPB49) Antibodies
- Dematin (EPB49) (erythrocyte Membrane Protein Band 4.9 (Dematin) (EPB49))
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Binding Specificity
- Middle Region
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Reactivity
- Human, Mouse, Rat, Cow, Horse, Dog, Guinea Pig
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This Dematin antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- KKPPIYKQRE SVGGSPQTKH LIEDLIIESS KFPAAQPPDP NQPAKIETDY
- Predicted Reactivity
- Cow: 86%, Dog: 86%, Guinea Pig: 79%, Horse: 85%, Human: 100%, Mouse: 93%, Rat: 93%
- Characteristics
- This is a rabbit polyclonal antibody against EPB49. It was validated on Western Blot.
- Purification
- Affinity Purified
- Top Product
- Discover our top product EPB49 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 405 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- Dematin (EPB49) (erythrocyte Membrane Protein Band 4.9 (Dematin) (EPB49))
- Alternative Name
- EPB49 (EPB49 Products)
- Synonyms
- MGC80597 antibody, MGC108072 antibody, EPB49 antibody, DMT antibody, AI325486 antibody, Epb4.9 antibody, Epb49 antibody, dematin antibody, dematin actin binding protein L homeolog antibody, dematin actin binding protein antibody, dmtn.L antibody, DMTN antibody, dmtn antibody, Dmtn antibody
- Background
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Dematin, or EPB49, is an actin-bundling protein originally identified in the erythroid membrane skeleton. Its actin-bundling activity is abolished upon phosphorylation by cAMP-dependent protein kinase and is restored after dephosphorylation.
Alias Symbols: DMT, FLJ78462, FLJ98848, EPB49
Protein Interaction Partner: GOLGA2, YWHAB, APP, NEDD4L, SNCA, PTOV1, DYNC1LI2, PRKACA, SNRPD2, PROCR, SPTB, EPB42, ACTB, ACTC1, DISC1,
Protein Size: 405 - Molecular Weight
- 45 kDa
- Gene ID
- 2039
- NCBI Accession
- NM_001978, NP_001969
- UniProt
- Q08495
- Pathways
- Regulation of Actin Filament Polymerization
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