EMR2 antibody (N-Term)

Catalog No. ABIN2788897

Product Details anti-EMR2 Antibody

Target: EMR2 (Egf-Like Module Containing, Mucin-Like, Hormone Receptor-Like 2 (EMR2))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Dog, Rabbit, Cow, Horse, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EMR2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: YDCVCSPGYE PVSGAKTFKN ESENTCQDVD ECQQNPRLCK SYGTCVNTLG

Predicted Reactivity: Cow: 86%, Dog: 86%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 93%, Rabbit: 79%

Characteristics: This is a rabbit polyclonal antibody against EMR2. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 812 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for EMR2

Target: EMR2 (Egf-Like Module Containing, Mucin-Like, Hormone Receptor-Like 2 (EMR2))

Alternative Name: EMR2 (EMR2 Products)

Synonyms: EMR2 antibody, CD312 antibody, adhesion G protein-coupled receptor E2 antibody, ADGRE2 antibody, LOC484898 antibody

Background: This gene encodes a member of the class B seven-span transmembrane (TM7) receptor family expressed predominantly by cells of the immune system. Family members are characterized by an extended extracellular region with a variable number of N-terminal epidermal growth factor (EGF)-like domains coupled to a TM7 domain via a mucin-like spacer domain. This gene is closely linked to the gene encoding egf-like molecule containing mucin-like hormone receptor 3 on chromosome 19. This protein does not interact with the ligand decay accelerating factor for complement, unlike the related CD97 antigen, and indicates that these very closely related proteins likely have nonredundant functions. This gene results in multiple transcripts encoding distinct isoforms.
Alias Symbols: CD312, DKFZp781B135
Protein Interaction Partner: UBC,
Protein Size: 812

Molecular Weight: 89 kDa

Gene ID: 30817

NCBI Accession: NM_152919, NP_690883