SPTBN1 antibody (C-Term)

Catalog No. ABIN2788921

Product Details anti-SPTBN1 Antibody

Target: SPTBN1 (Spectrin Beta, Non-Erythrocytic 1 (SPTBN1))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Dog, Cow, Horse, Guinea Pig, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SPTBN1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: DKHEVSASTQ STPASSRAQT LPTSVVTITS ESSPGKREKD KEKDKEKRFS

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 90%

Characteristics: This is a rabbit polyclonal antibody against SPTBN1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of human SPTBN1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for SPTBN1

Target: SPTBN1 (Spectrin Beta, Non-Erythrocytic 1 (SPTBN1))

Alternative Name: SPTBN1 (SPTBN1 Products)

Synonyms: 9930031C03Rik antibody, AL033301 antibody, SPTB2 antibody, Spnb-2 antibody, Spnb2 antibody, elf1 antibody, elf3 antibody, mKIAA4049 antibody, ELF antibody, betaSpII antibody, Spnb1 antibody, spectrin beta, non-erythrocytic 1 antibody, spectrin, beta, non-erythrocytic 1 antibody, Sptbn1 antibody, SPTBN1 antibody

Background: Spectrin is an actin crosslinking and molecular scaffold protein that links the plasma membrane to the actin cytoskeleton, and functions in the determination of cell shape, arrangement of transmembrane proteins, and organization of organelles. It is composed of two antiparallel dimers of alpha- and beta- subunits. This gene is one member of a family of beta-spectrin genes. The encoded protein contains an N-terminal actin-binding domain, and 17 spectrin repeats which are involved in dimer formation. Multiple transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: ELF, SPTB2, HEL102, betaSpII
Protein Size: 354

Molecular Weight: 38 kDa

Gene ID: 6711

NCBI Accession: NM_003128, NP_003119

UniProt: Q01082

Pathways: Regulation of Actin Filament Polymerization, Protein targeting to Nucleus