ARFGAP3 antibody (C-Term)

Catalog No. ABIN2788930

The Rabbit Polyclonal anti-ARFGAP3 antibody (ABIN2788930) specifically detects ARFGAP3 in WB. The antibody is reactive with Human, Rat, Dog, Cow, Horse and Pig samples.

Quick Overview for ARFGAP3 antibody (C-Term) (ABIN2788930)

Target: ARFGAP3 (ADP-Ribosylation Factor GTPase Activating Protein 3 (ARFGAP3))

Reactivity: Human, Rat, Dog, Cow, Horse, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ARFGAP3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ARFGAP3 Antibody

Binding Specificity: C-Term

Purpose: ARFGAP3 Antibody - C-terminal region

Sequence: SYWKKETSKD TETVLKTTGY SDRPTARRKP DYEPVENTDE AQKKFGNVKA

Predicted Reactivity: Cow: 86%, Dog: 100%, Horse: 93%, Human: 100%, Pig: 79%, Rat: 86%

Characteristics: This is a rabbit polyclonal antibody against ARFGAP3. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP61868-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for ARFGAP3

Target: ARFGAP3 (ADP-Ribosylation Factor GTPase Activating Protein 3 (ARFGAP3))

Alternative Name: ARFGAP3

Background:

Background Information: The protein encoded by this gene is a GTPase-activating protein (GAP) that associates with the Golgi apparatus and regulates the early secretory pathway of proteins. The encoded protein promotes hydrolysis of ADP-ribosylation factor 1 (ARF1)-bound GTP, which is required for the dissociation of coat proteins from Golgi-derived membranes and vesicles. Dissociation of the coat proteins is a prerequisite for the fusion of these vesicles with target compartments. The activity of this protein is sensitive to phospholipids. Multiple transcript variants encoding different isoforms have been found for this gene. This gene was originally known as ARFGAP1, but that is now the name of a related but different gene.

Gene Name: ADP-ribosylation factor GTPase activating protein 3

Alternative Symbols: ARFGAP1

Protein Name: ADP-ribosylation factor GTPase-activating protein 3

Molecular Weight: 57kDa

Gene ID: 26286

NCBI Accession: NP_055385

UniProt: Q9NP61