Ataxin 10 antibody (C-Term)

Catalog No. ABIN2788939

This Rabbit Polyclonal antibody specifically detects Ataxin 10 in WB. It exhibits reactivity toward Human, Mouse, Rat, Guinea Pig, Dog, Cow, Rabbit and Horse.

Quick Overview for Ataxin 10 antibody (C-Term) (ABIN2788939)

Target: Ataxin 10 (ATXN10)

Reactivity: Human, Mouse, Rat, Guinea Pig, Dog, Cow, Rabbit, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Ataxin 10 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Ataxin 10 Antibody

Binding Specificity: C-Term

Sequence: LTEDNSQNQD LIAKMEEQGL ADASLLKKVG FEVEKKGEKL ILKSTRDTPK

Predicted Reactivity: Cow: 86%, Dog: 79%, Guinea Pig: 93%, Horse: 86%, Human: 100%, Mouse: 77%, Rabbit: 85%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against ATXN10. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 411 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Ataxin 10

Target: Ataxin 10 (ATXN10)

Alternative Name: ATXN10

Background: This gene encodes a protein that may function in neuron survival, neuron differentiation, and neuritogenesis. These roles may be carried out via activation of the mitogen-activated protein kinase cascade. Expansion of a pentanucleotide repeat in an intronic region of this locus has been associated with spinocerebellar ataxia, type 10. Alternatively spliced transcript variants have been described.
Alias Symbols: E46L, FLJ37990, HUMEEP, SCA10
Protein Interaction Partner: UBC, HSPA8, HSPA1A, SERPINH1, EGFR, vpu, VCP, CA9, UBD, MRPS16, PPP1R12A, GOLGA1, GNB2, GNB1, GLS, FN1, ABCA1, CUL3, GSTK1, STYXL1, MAGED1, BSG,
Protein Size: 411

Molecular Weight: 45 kDa

Gene ID: 25814

NCBI Accession: NM_001167621, NP_001161093

UniProt: A6NLC4