HYAL3 antibody (C-Term)

Catalog No. ABIN2788944

The Rabbit Polyclonal anti-HYAL3 antibody is suitable to detect HYAL3 in samples from Human, Rat, Mouse, Guinea Pig, Horse, Pig, Rabbit, Cow, Dog and Sheep. It has been validated for WB.

Quick Overview for HYAL3 antibody (C-Term) (ABIN2788944)

Target: HYAL3 (Hyaluronidase-3 (HYAL3))

Reactivity: Human, Rat, Mouse, Guinea Pig, Horse, Pig, Rabbit, Cow, Dog, Sheep

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HYAL3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-HYAL3 Antibody

Binding Specificity: C-Term

Purpose: HYAL3 Antibody - C-terminal region

Sequence: RAAMACSHQR CHGHGRCARR DPGQMEAFLH LWPDGSLGDW KSFSCHCYWG

Predicted Reactivity: Cow: 90%, Dog: 90%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 90%, Rabbit: 79%, Rat: 86%, Sheep: 90%

Characteristics: This is a rabbit polyclonal antibody against HYAL3. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP61904-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for HYAL3

Target: HYAL3 (Hyaluronidase-3 (HYAL3))

Alternative Name: HYAL3

Background:

Background Information: This gene encodes a member of the hyaluronidase family. Hyaluronidases are endoglycosidase enzymes that degrade hyaluronan, one of the major glycosaminoglycans of the extracellular matrix. The regulated turnover of hyaluronan plays a critical role in many biological processes including cell proliferation, migration and differentiation. The encoded protein may also play an important role in sperm function. This gene is one of several related genes in a region of chromosome 3p21.3 associated with tumor suppression, and the expression of specific transcript variants may be indicative of tumor status.

Gene Name: Hyaluronoglucosaminidase 3

Alternative Symbols: LUCA3, HYAL-3, LUCA-3

Protein Name: Hyaluronidase-3

Molecular Weight: 46kDa

Gene ID: 8372

NCBI Accession: NP_003540

UniProt: O43820

Pathways: Glycosaminoglycan Metabolic Process