HMGN3 antibody (Middle Region)

Catalog No. ABIN2788960

The Rabbit Polyclonal anti-HMGN3 antibody (ABIN2788960) specifically detects HMGN3 in WB. The antibody is reactive with Human, Mouse, Rat, Horse, Dog, Guinea Pig, Rabbit and Cow samples.

Quick Overview for HMGN3 antibody (Middle Region) (ABIN2788960)

Target: HMGN3 (High Mobility Group Nucleosomal Binding Domain 3 (HMGN3))

Reactivity: Human, Mouse, Rat, Horse, Dog, Guinea Pig, Rabbit, Cow

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HMGN3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-HMGN3 Antibody

Binding Specificity: Middle Region

Purpose: HMGN3 Antibody - middle region

Sequence: KTSAKKEPGA KISRGAKGKK EEKQEAGKEG TAPSENGETK AEEVLSINTS

Predicted Reactivity: Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against HMGN3. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP61955-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for HMGN3

Target: HMGN3 (High Mobility Group Nucleosomal Binding Domain 3 (HMGN3))

Alternative Name: HMGN3

Background:

Background Information: Thyroid hormone receptors are hormone-dependent transcription factors that regulate expression of a variety of specific target genes. The protein encoded by this gene binds thyroid hormone receptor beta, but only in the presence of thyroid hormone. The encoded protein, a member of the HMGN protein family, is thought to reduce the compactness of the chromatin fiber in nucleosomes, thereby enhancing transcription from chromatin templates. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene Name: High mobility group nucleosomal binding domain 3

Alternative Symbols: TRIP7, PNAS-24, PNAS-25

Protein Name: High mobility group nucleosome-binding domain-containing protein 3

Molecular Weight: 10kDa

Gene ID: 9324

NCBI Accession: NP_001188291

UniProt: Q15651