EIF3F antibody (C-Term)

Catalog No. ABIN2788968

This anti-EIF3F antibody is a Rabbit Polyclonal antibody detecting EIF3F in WB. Suitable for Human, Mouse, Rat, Cow, Rabbit, Dog, Horse and Zebrafish (Danio rerio).

Quick Overview for EIF3F antibody (C-Term) (ABIN2788968)

Target: EIF3F (Eukaryotic Translation Initiation Factor 3 Subunit F (EIF3F))

Reactivity: Human, Mouse, Rat, Cow, Rabbit, Dog, Horse, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EIF3F antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-EIF3F Antibody

Binding Specificity: C-Term

Sequence: IQDALSTVLQ YAEDVLSGKV SADNTVGRFL MSLVNQVPKI VPDDFETMLN

Predicted Reactivity: Cow: 100%, Dog: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%

Characteristics: This is a rabbit polyclonal antibody against EIF3F. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 357 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for EIF3F

Target: EIF3F (Eukaryotic Translation Initiation Factor 3 Subunit F (EIF3F))

Alternative Name: EIF3F

Background: EIF3F is a component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of posttermination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation.
Alias Symbols: EIF3S5, eIF3-p47
Protein Interaction Partner: HUWE1, UBC, SUMO2, RNF2, FBXO6, RPS6KB1, IGSF8, ICAM1, CD81, DDX3X, gag-pol, EIF3D, EIF3B, ATXN1, SMAD9, FN1, EIF3M, EIF3C, EIF3A, MSMO1, EIF3E, ATP6V1A, APP, EIF3L, EIF3K, MRPL46, EIF3I, EIF3H, EIF3G, UBD, HNRNPK, CDK11B, YWHAZ, NOTCH1, DTX1, RAD21, FBXO
Protein Size: 357

Molecular Weight: 39 kDa

Gene ID: 8665

NCBI Accession: NM_003754, NP_003745

UniProt: O00303

Pathways: Ribonucleoprotein Complex Subunit Organization