CES3 antibody (C-Term)

Catalog No. ABIN2788984

The Rabbit Polyclonal anti-CES3 antibody (ABIN2788984) specifically detects CES3 in WB. The antibody is reactive with Human and Pig samples.

Quick Overview for CES3 antibody (C-Term) (ABIN2788984)

Target: CES3 (Carboxylesterase 3 (CES3))

Reactivity: Human, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CES3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CES3 Antibody

Binding Specificity: C-Term

Purpose: CES3 Antibody - C-terminal region

Sequence: QAEQYLEINP VPRAGQKFRE AWMQFWSETL PSKIQQWHQK QKNRKAQEDL

Predicted Reactivity: Human: 100%, Pig: 79%

Characteristics: This is a rabbit polyclonal antibody against CES3. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP62006-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for CES3

Target: CES3 (Carboxylesterase 3 (CES3))

Alternative Name: CES3

Background:

Background Information: This gene encodes a member of the carboxylesterase large family. The family members are responsible for the hydrolysis or transesterification of various xenobiotics, such as cocaine and heroin, and endogenous substrates with ester, thioester, or amide bonds. They may participate in fatty acyl and cholesterol ester metabolism, and may play a role in the blood-brain barrier system. This gene is expressed in several tissues, particularly in colon, trachea and in brain, and the protein participates in colon and neural drug metabolism. Multiple alternatively spliced transcript variants encoding distinct isoforms have been reported, but the biological validity and/or full-length nature of some variants have not been determined.

Gene Name: Carboxylesterase 3

Alternative Symbols: ES31

Protein Name: Carboxylesterase 3

Molecular Weight: 63kDa

Gene ID: 23491

NCBI Accession: NP_079198

UniProt: Q6UWW8

Pathways: Monocarboxylic Acid Catabolic Process