ACOT8 antibody (N-Term)
Quick Overview for ACOT8 antibody (N-Term) (ABIN2789001)
Target
See all ACOT8 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- N-Term
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Sequence
- SSPQAPEDGQ GCGDRGDPPG DLRSVLVTTV LNLEPLDEDL FRGRHYWVPA
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Predicted Reactivity
- Human: 100%
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Characteristics
- This is a rabbit polyclonal antibody against ACOT8. It was validated on Western Blot.
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Purification
- Affinity Purified
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Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
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Comment
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Antigen size: 319 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- ACOT8 (Acyl-CoA Thioesterase 8 (ACOT8))
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Alternative Name
- ACOT8
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Background
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The protein encoded by this gene is a peroxisomal thioesterase that appears to be involved more in the oxidation of fatty acids rather than in their formation. The encoded protein can bind to the human immunodeficiency virus-1 protein Nef, and mediate Nef-induced down-regulation of CD4 in T-cells.
Alias Symbols: HNAACTE, PTE-2, PTE1, PTE2, hACTE-III, hTE, PTE-1
Protein Interaction Partner: REL, PEX5, UBC, NEDD8, SUMO1, RNF2, nef, US3, ISG15, MYC,
Protein Size: 319 -
Molecular Weight
- 35 kDa
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Gene ID
- 10005
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NCBI Accession
- NM_005469, NP_005460
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UniProt
- O14734
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Pathways
- Monocarboxylic Acid Catabolic Process
Target
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