HOOK1 antibody (C-Term)

Catalog No. ABIN2789012

The Rabbit Polyclonal anti-HOOK1 antibody has been validated for WB. It is suitable to detect HOOK1 in samples from Human, Mouse, Rat, Guinea Pig, Cow, Dog, Horse, Pig and Rabbit.

Quick Overview for HOOK1 antibody (C-Term) (ABIN2789012)

Target: HOOK1 (Hook Homolog 1 (HOOK1))

Reactivity: Human, Mouse, Rat, Guinea Pig, Cow, Dog, Horse, Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HOOK1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-HOOK1 Antibody

Binding Specificity: C-Term

Sequence: REVFIRLQHE NKMLRLQQEG SENERIEELQ EQLEQKHRKM NELETEQRLS

Predicted Reactivity: Cow: 93%, Dog: 93%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 86%, Pig: 93%, Rabbit: 93%, Rat: 86%

Characteristics: This is a rabbit polyclonal antibody against HOOK1. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 728 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for HOOK1

Target: HOOK1 (Hook Homolog 1 (HOOK1))

Alternative Name: HOOK1

Background: This gene encodes a member of the hook family of coiled-coil proteins, which bind to microtubules and organelles through their N- and C-terminal domains, respectively. The encoded protein localizes to discrete punctuate subcellular structures, and interacts with several members of the Rab GTPase family involved in endocytosis. It is thought to link endocytic membrane trafficking to the microtubule cytoskeleton. Several alternatively spliced transcript variants have been identified, but the full-length nature of some of these variants has not been determined.
Alias Symbols: HK1, MGC10642
Protein Interaction Partner: AKTIP, HOOK1, TBC1D7, TFIP11, USP2, LMO2, CDK4, ZNF785, SYCE1, VCP, HOOK3, FAM160A2, VPS16, VPS18, HOOK2, VPS41, VPS39, UBC, CDC5L, ZNF250, ANK3,
Protein Size: 728

Molecular Weight: 80 kDa

Gene ID: 51361

NCBI Accession: NM_015888, NP_056972

UniProt: Q9UJC3

Pathways: SARS-CoV-2 Protein Interactome