BTLA antibody (C-Term)

Catalog No. ABIN2789021

This anti-BTLA antibody is a Rabbit Polyclonal antibody detecting BTLA in WB. Suitable for Human and Horse.

Quick Overview for BTLA antibody (C-Term) (ABIN2789021)

Target: BTLA (B and T Lymphocyte Associated (BTLA))

Reactivity: Human, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BTLA antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-BTLA Antibody

Binding Specificity: C-Term

Sequence: SRPWLLYSLL PLGGLPLLIT TCFCLFCCLR RHQGKQNELS DTAGREINLV

Predicted Reactivity: Horse: 79%, Human: 100%

Characteristics: This is a rabbit polyclonal antibody against BTLA. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 289 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for BTLA

Target: BTLA (B and T Lymphocyte Associated (BTLA))

Alternative Name: BTLA

Background: This gene encodes a member of the immunoglobulin superfamily. The encoded protein contains a single immunoglobulin (Ig) domain and is a receptor that relays inhibitory signals to suppress the immune response. Alternative splicing results in multiple transcript variants. Polymorphisms in this gene have been associated with an increased risk of rheumatoid arthritis.
Alias Symbols: BTLA1, CD272, FLJ16065, MGC129743
Protein Interaction Partner: TNFRSF14, VTCN1, PTPN6, PTPN11,
Protein Size: 289

Molecular Weight: 32 kDa

Gene ID: 151888

NCBI Accession: NM_181780, NP_861445

UniProt: Q7Z6A9

Pathways: Cancer Immune Checkpoints