BTLA antibody
Quick Overview for BTLA antibody (ABIN7505891)
Target
See all BTLA AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Purpose
- Anti-Hu CD272 Purified
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Characteristics
- The mouse monoclonal antibody MIH26 recognizes an extracellular epitope of CD272, a transmembrane glycoprotein serving as a negative regulator of the activation in various leukocyte types.
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Purification
- Purified by protein-A affinity chromatography.
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Immunogen
- cells transfected with human CD272
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Isotype
- IgG2a, kappa
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anti-B and T Lymphocyte Associated (BTLA) antibody
BTLA Reactivity: Human WB, FACS Host: Mouse Monoclonal 2E4 unconjugated
anti-B and T Lymphocyte Associated (BTLA) (AA 30-183) antibodyBTLA Reactivity: Mouse WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-B and T Lymphocyte Associated (BTLA) (AA 31-157) antibodyBTLA Reactivity: Human FACS, ELISA Host: Mouse Monoclonal 5G1G10 unconjugated
anti-B and T Lymphocyte Associated (BTLA) (AA 31-157) antibodyBTLA Reactivity: Human ELISA, ICC Host: Mouse Monoclonal 7B8B4 unconjugated
anti-B and T Lymphocyte Associated (BTLA) (AA 179-289) antibodyBTLA Reactivity: Human FACS, ELISA Host: Mouse Monoclonal 4B12A7 unconjugated
anti-B and T Lymphocyte Associated (BTLA) antibodyBTLA Reactivity: Human WB, IHC, IF, IHC (p) Host: Mouse Monoclonal 4D6 unconjugated
anti-B and T Lymphocyte Associated (BTLA) antibodyBTLA Reactivity: Human WB, FACS, IF Host: Mouse Monoclonal 2G2 unconjugated
anti-B and T Lymphocyte Associated (BTLA) (AA 221-289) antibodyBTLA Reactivity: Human, Mouse WB, FACS, ELISA, ICC, IF (cc), IF (p), IHC (p), IHC (fro) Host: Rabbit Polyclonal unconjugated
anti-B and T Lymphocyte Associated (BTLA) (AA 30-183) antibodyBTLA Reactivity: Rat WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-B and T Lymphocyte Associated (BTLA) (AA 190-289) antibodyBTLA Reactivity: Human WB, ELISA, IF Host: Mouse Monoclonal 4B8 unconjugated
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Application Notes
- Flow cytometry: Recommended dilution: 2-5 μg/mL.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Do not freeze
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Storage
- 4 °C
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Storage Comment
- Store at 2-8°C. Do not freeze.
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- BTLA (B and T Lymphocyte Associated (BTLA))
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Alternative Name
- CD272
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Background
- B and T lymphocyte associated,CD272, a type I transmembrane glycoprotein, contains in its intracellular domain two ITIM sequences, which are upon CD272 triggering phosphorylated and recruit SHP phosphatases to attenuate cell activation. CD272 is expressed on B and T lymphocytes, NK cells, dendritic cells, and macrophages, and its ligand is CD270. Defects in CD272-CD270 inhibitory mechanism lead to autoimmune diseases. Overexpression of CD272 is a marker of tolerant T cells.,BTLA1
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Gene ID
- 151888
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UniProt
- Q7Z6A9
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Pathways
- Cancer Immune Checkpoints
Target
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