BTLA antibody (C-Term)

Catalog No. ABIN2789021

The Rabbit Polyclonal anti-BTLA antibody (ABIN2789021) specifically detects BTLA in WB. The antibody is reactive with Human and Horse samples.

Quick Overview for BTLA antibody (C-Term) (ABIN2789021)

Target: BTLA (B and T Lymphocyte Associated (BTLA))

Reactivity: Human, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BTLA antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-BTLA Antibody

Binding Specificity: C-Term

Purpose: BTLA Antibody - C-terminal region

Sequence: SRPWLLYSLL PLGGLPLLIT TCFCLFCCLR RHQGKQNELS DTAGREINLV

Predicted Reactivity: Horse: 79%, Human: 100%

Characteristics: This is a rabbit polyclonal antibody against BTLA. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP62109-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for BTLA

Target: BTLA (B and T Lymphocyte Associated (BTLA))

Alternative Name: BTLA

Background:

Background Information: This gene encodes a member of the immunoglobulin superfamily. The encoded protein contains a single immunoglobulin (Ig) domain and is a receptor that relays inhibitory signals to suppress the immune response. Alternative splicing results in multiple transcript variants. Polymorphisms in this gene have been associated with an increased risk of rheumatoid arthritis.

Gene Name: B and T lymphocyte associated

Alternative Symbols: BTLA1, CD272

Protein Name: B- and T-lymphocyte attenuator

Molecular Weight: 32kDa

Gene ID: 151888

NCBI Accession: NP_861445

UniProt: Q7Z6A9

Pathways: Cancer Immune Checkpoints