CHMP2A antibody (C-Term)

Catalog No. ABIN2789024

The Rabbit Polyclonal anti-CHMP2A antibody has been validated for WB. It is suitable to detect CHMP2A in samples from Human, Rat, Mouse, Cow, Guinea Pig, Rabbit, Dog, Zebrafish (Danio rerio) and Horse.

Quick Overview for CHMP2A antibody (C-Term) (ABIN2789024)

Target: CHMP2A (Charged Multivesicular Body Protein 2A (CHMP2A))

Reactivity: Human, Rat, Mouse, Cow, Guinea Pig, Rabbit, Dog, Zebrafish (Danio rerio), Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CHMP2A antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CHMP2A Antibody

Binding Specificity: C-Term

Sequence: DELGLSLTDE LSNLPSTGGS LSVAAGGKKA EAAASALADA DADLEERLKN

Predicted Reactivity: Cow: 100%, Dog: 93%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 92%

Characteristics: This is a rabbit polyclonal antibody against CHMP2A. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 222 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CHMP2A

Target: CHMP2A (Charged Multivesicular Body Protein 2A (CHMP2A))

Alternative Name: CHMP2A

Background: CHMP2A belongs to the chromatin-modifying protein/charged multivesicular body protein (CHMP) family. These proteins are components of ESCRT-III (endosomal sorting complex required for transport III), a complex involved in degradation of surface receptor proteins and formation of endocytic multivesicular bodies (MVBs). Some CHMPs have both nuclear and cytoplasmic/vesicular distributions, and one such CHMP, CHMP1A (MIM 164010), is required for both MVB formation and regulation of cell cycle progression.
Alias Symbols: BC-2, BC2, CHMP2, VPS2, VPS2A
Protein Interaction Partner: DOCK8, UBC, TGFB3, ITGA4, E2F4, ERLIN1, RRBP1, RANBP2, PPP1CA, CHMP3, CHMP2A, VPS4A, EIF2B5, NOL4, MITD1, USP54, USP8, VPS4B, VTA1, STAMBP,
Protein Size: 222

Molecular Weight: 24 kDa

Gene ID: 27243

NCBI Accession: NM_014453, NP_055268

UniProt: O43633

Pathways: SARS-CoV-2 Protein Interactome