HOMER3 antibody (C-Term)

Catalog No. ABIN2789049

This anti-HOMER3 antibody is a Rabbit Polyclonal antibody detecting HOMER3 in WB. Suitable for Human, Mouse, Rat, Dog, Horse, Cow, Pig and Saccharomyces cerevisiae.

Quick Overview for HOMER3 antibody (C-Term) (ABIN2789049)

Target: HOMER3 (Homer Homolog 3 (Drosophila) (HOMER3))

Reactivity: Human, Mouse, Rat, Dog, Horse, Cow, Pig, Saccharomyces cerevisiae

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HOMER3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-HOMER3 Antibody

Binding Specificity: C-Term

Sequence: HQLRAMERSL EEARAERERA RAEVGRAAQL LDVSLFELSE LREGLARLAE

Predicted Reactivity: Cow: 93%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 93%, Rat: 100%, Yeast: 100%

Characteristics: This is a rabbit polyclonal antibody against HOMER3. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 358 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for HOMER3

Target: HOMER3 (Homer Homolog 3 (Drosophila) (HOMER3))

Alternative Name: HOMER3

Background: This gene encodes a member of the HOMER family of postsynaptic density scaffolding proteins that share a similar domain structure consisting of an N-terminal Enabled/vasodilator-stimulated phosphoprotein homology 1 domain which mediates protein-protein interactions, and a carboxy-terminal coiled-coil domain and two leucine zipper motifs that are involved in self-oligomerization. The encoded protein binds numerous other proteins including group I metabotropic glutamate receptors, inositol 1,4,5-trisphosphate receptors and amyloid precursor proteins and has been implicated in diverse biological functions such as neuronal signaling, T-cell activation and trafficking of amyloid beta peptides. Alternative splicing results in multiple transcript variants.
Alias Symbols: HOMER-3, VESL3
Protein Interaction Partner: PPP1R18, EAF1, NEBL, ABI2, POM121, HOMER1, HOMER3, USP2, EIF3D, WIPF1, SNRPF, PSMA1, PKN1, MOS, RUNX1T1, SRPK2, Grm5, Homer2, ABI3, PSMA2, APP, Pax6, IKBKB, PSMC5, Cdc16, Snw1, DYNLL2, FAT1, CEBPB, RYR1, ITPR1, TRPC5, TRPC4, TRPC1, FRYL,
Protein Size: 358

Molecular Weight: 39 kDa

Gene ID: 9454

NCBI Accession: NM_001145721, NP_001139193

UniProt: Q9NSC5