HOMER3 antibody (N-Term)

Catalog No. ABIN2789050

This Rabbit Polyclonal antibody specifically detects HOMER3 in WB. It exhibits reactivity toward Human, Mouse, Rat, Dog, Horse, Cow and Guinea Pig.

Quick Overview for HOMER3 antibody (N-Term) (ABIN2789050)

Target: HOMER3 (Homer Homolog 3 (Drosophila) (HOMER3))

Reactivity: Human, Mouse, Rat, Dog, Horse, Cow, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HOMER3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-HOMER3 Antibody

Binding Specificity: N-Term

Sequence: DSRANTVYGL GFASEQHLTQ FAEKFQEVKE AARLAREKSQ DGGELTSPAL

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 93%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against HOMER3. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 358 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for HOMER3

Target: HOMER3 (Homer Homolog 3 (Drosophila) (HOMER3))

Alternative Name: HOMER3

Background: This gene encodes a member of the HOMER family of postsynaptic density scaffolding proteins that share a similar domain structure consisting of an N-terminal Enabled/vasodilator-stimulated phosphoprotein homology 1 domain which mediates protein-protein interactions, and a carboxy-terminal coiled-coil domain and two leucine zipper motifs that are involved in self-oligomerization. The encoded protein binds numerous other proteins including group I metabotropic glutamate receptors, inositol 1,4,5-trisphosphate receptors and amyloid precursor proteins and has been implicated in diverse biological functions such as neuronal signaling, T-cell activation and trafficking of amyloid beta peptides. Alternative splicing results in multiple transcript variants.
Alias Symbols: HOMER-3, VESL3
Protein Interaction Partner: PPP1R18, EAF1, NEBL, ABI2, POM121, HOMER1, HOMER3, USP2, EIF3D, WIPF1, SNRPF, PSMA1, PKN1, MOS, RUNX1T1, SRPK2, Grm5, Homer2, ABI3, PSMA2, APP, Pax6, IKBKB, PSMC5, Cdc16, Snw1, DYNLL2, FAT1, CEBPB, RYR1, ITPR1, TRPC5, TRPC4, TRPC1, FRYL,
Protein Size: 358

Molecular Weight: 39 kDa

Gene ID: 9454

NCBI Accession: NM_001145721, NP_001139193

UniProt: Q9NSC5