HRH3 antibody (C-Term)

Catalog No. ABIN2789051

The Rabbit Polyclonal anti-HRH3 antibody (ABIN2789051) specifically detects HRH3 in WB. The antibody is reactive with Human, Mouse, Rat, Cow, Horse, Guinea Pig, Dog and Rabbit samples.

Quick Overview for HRH3 antibody (C-Term) (ABIN2789051)

Target: HRH3 (Histamine Receptor H3 (HRH3))

Reactivity: Human, Mouse, Rat, Cow, Horse, Guinea Pig, Dog, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HRH3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-HRH3 Antibody

Binding Specificity: C-Term

Purpose: HRH3 Antibody - C-terminal region

Sequence: LGGGGGGGSV ASPTSSSGSS SRGTERPRSL KRGSKPSASS ASLEKRMKMV

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against HRH3. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human HRH3

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP62179-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for HRH3

Target: HRH3 (Histamine Receptor H3 (HRH3))

Alternative Name: HRH3

Background:

Background Information: Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by histamine receptors H1, H2, H3 and H4. This gene encodes one of the histamine receptors (H3) which belongs to the family 1 of G protein-coupled receptors. It is an integral membrane protein and can regulate neurotransmitter release. This receptor can also increase voltage-dependent calcium current in smooth muscles and innervates the blood vessels and the heart in cardiovascular system.

Gene Name: histamine receptor H3

Alternative Symbols: HH3R, GPCR97

Protein Name: Histamine H3 receptor

Molecular Weight: 45kDa

Gene ID: 11255

UniProt: Q9Y5N1

Pathways: cAMP Metabolic Process, Feeding Behaviour