MTMR6 antibody (C-Term)
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- Target See all MTMR6 Antibodies
- MTMR6 (Myotubularin Related Protein 6 (MTMR6))
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Binding Specificity
- C-Term
- Reactivity
- Human, Rat, Guinea Pig, Horse, Rabbit, Dog
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This MTMR6 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- KDLESKIKQR KNKQTDGILT KELLHSVHPE SPNLKTSLCF KEQTLLPVND
- Predicted Reactivity
- Dog: 93%, Guinea Pig: 86%, Horse: 86%, Human: 100%, Rabbit: 86%, Rat: 79%
- Characteristics
- This is a rabbit polyclonal antibody against MTMR6. It was validated on Western Blot.
- Purification
- Affinity Purified
- Top Product
- Discover our top product MTMR6 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 621 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- MTMR6 (Myotubularin Related Protein 6 (MTMR6))
- Alternative Name
- MTMR6 (MTMR6 Products)
- Synonyms
- 4022440C11Rik antibody, AI428804 antibody, AU041072 antibody, zgc:55289 antibody, wu:fi04a11 antibody, si:dkey-286f3.1 antibody, zgc:56405 antibody, myotubularin related protein 6 antibody, myotubularin related protein 8 antibody, MTMR6 antibody, Mtmr6 antibody, mtmr6 antibody, mtmr8 antibody
- Background
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MTMR6 phosphatase that acts on lipids with a phosphoinositol headgroup. It acts as a negative regulator of KCNN4/KCa3.1 channel activity in CD4+ T-cells possibly by decreasing intracellular levels of phosphatidylinositol-3 phosphatase. It negatively regulates proliferation of reactivated CD4+ T-cells.
Alias Symbols: -
Protein Interaction Partner: MTMR9, AMOTL2, MTUS2, NMI, TRIM27, UBC, RARG, UBD, ELAVL1,
Protein Size: 621 - Molecular Weight
- 68 kDa
- Gene ID
- 9107
- NCBI Accession
- NM_004685, NP_004676
- UniProt
- Q9Y217
- Pathways
- Inositol Metabolic Process
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