NSL1 antibody (C-Term)

Catalog No. ABIN2789054

Product Details anti-NSL1 Antibody

Target: NSL1 (NSL1, MIND Kinetochore Complex Component, Homolog (NSL1))

Binding Specificity: C-Term

Reactivity: Human, Cow

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NSL1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: PALIEQGEGF SQVLRMQPVI HLQRIHQEVF SSCHRKPDAK PENFITQIET

Predicted Reactivity: Cow: 79%, Human: 100%

Characteristics: This is a rabbit polyclonal antibody against NSL1. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 281 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for NSL1

Target: NSL1 (NSL1, MIND Kinetochore Complex Component, Homolog (NSL1))

Alternative Name: NSL1 (NSL1 Products)

Synonyms: 4833432M17Rik antibody, AI451597 antibody, Gm105 antibody, Gm984 antibody, C1orf48 antibody, MIS14 antibody, NSL1, MIS12 kinetochore complex component antibody, NSL1, MIS12 kinetochore complex component L homeolog antibody, NSL1 antibody, nsl1.L antibody, nsl1 antibody, Nsl1 antibody

Background: This gene encodes a protein with two coiled-coil domains that localizes to kinetochores, which are chromosome-associated structures that attach to microtubules and mediate chromosome movements during cell division. The encoded protein is part of a conserved protein complex that includes two chromodomain-containing proteins and a component of the outer plate of the kinetochore. This protein complex is proposed to bridge centromeric heterochromatin with the outer kinetochore structure. Multiple transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: C1orf48, DC8, DKFZp566O1646, MIS14
Protein Interaction Partner: UBC, SUGT1, G6PC, CBX5, NDC80, MIS12, CASC5, NSL1, ZWINT, NF1, BUB1, HSP90AA1, DSN1, SGOL1, CBX3, CBX1, AURKB, MAD2L1, BUB1B,
Protein Size: 281

Molecular Weight: 31 kDa

Gene ID: 25936

NCBI Accession: NM_015471, NP_056286

UniProt: Q96IY1