NSL1 antibody (C-Term)

Catalog No. ABIN2789054

This Rabbit Polyclonal antibody specifically detects NSL1 in WB. It exhibits reactivity toward Human and Cow.

Quick Overview for NSL1 antibody (C-Term) (ABIN2789054)

Target: NSL1 (NSL1, MIND Kinetochore Complex Component, Homolog (NSL1))

Reactivity: Human, Cow

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NSL1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-NSL1 Antibody

Binding Specificity: C-Term

Purpose: NSL1 Antibody - C-terminal region

Sequence: PALIEQGEGF SQVLRMQPVI HLQRIHQEVF SSCHRKPDAK PENFITQIET

Predicted Reactivity: Cow: 79%, Human: 100%

Characteristics: This is a rabbit polyclonal antibody against NSL1. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP62184-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for NSL1

Target: NSL1 (NSL1, MIND Kinetochore Complex Component, Homolog (NSL1))

Alternative Name: NSL1

Background:

Background Information: This gene encodes a protein with two coiled-coil domains that localizes to kinetochores, which are chromosome-associated structures that attach to microtubules and mediate chromosome movements during cell division. The encoded protein is part of a conserved protein complex that includes two chromodomain-containing proteins and a component of the outer plate of the kinetochore. This protein complex is proposed to bridge centromeric heterochromatin with the outer kinetochore structure. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene Name: NSL1, MIND kinetochore complex component, homolog (S. cerevisiae)

Alternative Symbols: DC8, MIS14, C1orf48

Protein Name: Kinetochore-associated protein NSL1 homolog

Molecular Weight: 31kDa

Gene ID: 25936

NCBI Accession: NP_056286

UniProt: Q96IY1