ORC3 antibody (C-Term)
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- Target See all ORC3 Antibodies
- ORC3 (Origin Recognition Complex, Subunit 3 (ORC3))
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Binding Specificity
- C-Term
- Reactivity
- Human, Mouse, Cow, Dog, Rat, Pig, Rabbit, Zebrafish (Danio rerio), Saccharomyces cerevisiae, Horse, Guinea Pig
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This ORC3 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- VVTAAEKMDA NSATSEEMNE IIHARFIRAV SELELLGFIK PTKQKTDHVA
- Predicted Reactivity
- Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Yeast: 79%, Zebrafish: 86%
- Characteristics
- This is a rabbit polyclonal antibody against ORC3L. It was validated on Western Blot.
- Purification
- Affinity Purified
- Top Product
- Discover our top product ORC3 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 712 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- ORC3 (Origin Recognition Complex, Subunit 3 (ORC3))
- Alternative Name
- ORC3L (ORC3 Products)
- Synonyms
- CG4088 antibody, DmORC3 antibody, DmOrc3 antibody, Dmel\\CG4088 antibody, LAT antibody, ORC antibody, ORC3 antibody, Orc3 antibody, l(2)49Fd antibody, l(2)vr6 antibody, vr-6 antibody, vr6 antibody, ORC3L antibody, orc3 antibody, ATORC3 antibody, F5E19.30 antibody, F5E19_30 antibody, ORIGIN RECOGNITION COMPLEX SUBUNIT 3 antibody, origin recognition complex subunit 3 antibody, Afu8g04240 antibody, DDBDRAFT_0216767 antibody, DDBDRAFT_0233773 antibody, DDB_0216767 antibody, DDB_0233773 antibody, LOC100226325 antibody, LATHEO antibody, Orc3l antibody, Origin recognition complex subunit 3 antibody, origin recognition complex subunit 3 antibody, origin recognition complex, subunit 3 antibody, Orc3 antibody, ORC3 antibody, orc3 antibody, AFUA_8G04240 antibody, BDBG_01002 antibody, orcC antibody
- Background
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The origin recognition complex (ORC) is a highly conserved six subunits protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. The protein encoded by this gene is a subunit of the ORC complex. Studies of a similar gene in Drosophila suggested a possible role of this protein in neuronal proliferation and olfactory memory. Alternatively spliced transcript variants encoding distinct isoforms have been reported for this gene.
Alias Symbols: LAT, LATHEO, ORC3, ORC3L
Protein Interaction Partner: ORC5, ORC4, ORC1, MCM7, CDC6, MCM10, ORC6, CCNE2, CDC45, LRWD1, ORC2, APP, SUMO2, XRCC5, UBC, XRCC6, ZBP1, DBF4, ORC3, MCM5, CDK4, TERF2, BRCA1, MCM4,
Protein Size: 712 - Molecular Weight
- 82 kDa
- Gene ID
- 23595
- NCBI Accession
- NM_181837, NP_862820
- Pathways
- Mitotic G1-G1/S Phases, DNA Replication, Feeding Behaviour, Synthesis of DNA
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