NPLOC4 antibody (N-Term)

Catalog No. ABIN2789102

The Rabbit Polyclonal anti-NPLOC4 antibody (ABIN2789102) specifically detects NPLOC4 in WB. The antibody is reactive with Human, Mouse, Rat, Zebrafish (Danio rerio), Horse, Cow, Dog, Guinea Pig and Rabbit samples.

Quick Overview for NPLOC4 antibody (N-Term) (ABIN2789102)

Target: NPLOC4 (Nuclear Protein Localization 4 Homolog (NPLOC4))

Reactivity: Human, Mouse, Rat, Zebrafish (Danio rerio), Horse, Cow, Dog, Guinea Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NPLOC4 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-NPLOC4 Antibody

Binding Specificity: N-Term

Purpose: Nploc4 Antibody - N-terminal region

Sequence: GLKAFGAPNV VEDEIDQYLS KQDGKIYRSR DPQLCRHGPL GKCVHCVPLE

Predicted Reactivity: Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 86%

Characteristics: This is a rabbit polyclonal antibody against Nploc4. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Mouse Nploc4

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP62292-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for NPLOC4

Target: NPLOC4 (Nuclear Protein Localization 4 Homolog (NPLOC4))

Alternative Name: Nploc4

Background:

Background Information: The ternary complex containing UFD1L, VCP and NPLOC4 binds ubiquitinated proteins and is necessary for the export of misfolded proteins from the ER to the cytoplasm, where they are degraded by the proteasome. The NPLOC4-UFD1L-VCP complex regulates spindle disassembly at the end of mitosis and is necessary for the formation of a closed nuclear envelope.

Gene Name: nuclear protein localization 4 homolog (S. cerevisiae)

Alternative Symbols: Npl4, AK129375, mKIAA1499

Protein Name: Nuclear protein localization protein 4 homolog

Molecular Weight: 66kDa

Gene ID: 217365

NCBI Accession: NP_001181952

UniProt: P60670