ATP6V1C2 antibody (C-Term)

Catalog No. ABIN2789107

The Rabbit Polyclonal anti-ATP6V1C2 antibody (ABIN2789107) specifically detects ATP6V1C2 in WB. The antibody is reactive with Human, Mouse, Rat, Cow, Dog, Horse, Pig, Guinea Pig and Rabbit samples.

Quick Overview for ATP6V1C2 antibody (C-Term) (ABIN2789107)

Target: ATP6V1C2 (ATPase, H+ Transporting, Lysosomal 42kDa, V1 Subunit C2 (ATP6V1C2))

Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Pig, Guinea Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ATP6V1C2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ATP6V1C2 Antibody

Binding Specificity: C-Term

Sequence: SEAFIAWIHI KALRVFVESV LRYGLPVNFQ AVLLQPHKKS STKRLREVLN

Predicted Reactivity: Cow: 86%, Dog: 100%, Guinea Pig: 93%, Horse: 86%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 93%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against ATP6V1C2. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 381 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for ATP6V1C2

Target: ATP6V1C2 (ATPase, H+ Transporting, Lysosomal 42kDa, V1 Subunit C2 (ATP6V1C2))

Alternative Name: ATP6V1C2

Background: This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A,three B, and two G subunits, as well as a C, D, E, F, and H subunit. The V1 domain contains the ATP catalytic site. This gene encodes alternate transcriptional splice variants, encoding different V1 domain C subunit isoforms.
Alias Symbols: ATP6C2, VMA5
Protein Interaction Partner: GOLGA2,
Protein Size: 381

Molecular Weight: 42 kDa

Gene ID: 245973

NCBI Accession: NM_144583, NP_653184

UniProt: A8KA87

Pathways: Transition Metal Ion Homeostasis, Proton Transport