GADD45GIP1 antibody (Middle Region)

Catalog No. ABIN2789108

This Rabbit Polyclonal antibody specifically detects GADD45GIP1 in WB. It exhibits reactivity toward Human, Mouse, Rat, Dog, Guinea Pig, Rabbit, Cow, Horse, Pig and Saccharomyces cerevisiae.

Quick Overview for GADD45GIP1 antibody (Middle Region) (ABIN2789108)

Target: GADD45GIP1 (Growth Arrest and DNA-Damage-Inducible, gamma Interacting Protein 1 (GADD45GIP1))

Reactivity: Human, Mouse, Rat, Dog, Guinea Pig, Rabbit, Cow, Horse, Pig, Saccharomyces cerevisiae

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GADD45GIP1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-GADD45GIP1 Antibody

Binding Specificity: Middle Region

Sequence: SLRVKQLAEE QKRREREQHI AECMAKMPQM IVNWQQQQRE NWEKAQADKE

Predicted Reactivity: Cow: 90%, Dog: 90%, Guinea Pig: 85%, Horse: 90%, Human: 100%, Mouse: 90%, Pig: 92%, Rabbit: 85%, Rat: 92%, Yeast: 91%

Characteristics: This is a rabbit polyclonal antibody against GADD45GIP1. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 222 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for GADD45GIP1

Target: GADD45GIP1 (Growth Arrest and DNA-Damage-Inducible, gamma Interacting Protein 1 (GADD45GIP1))

Alternative Name: GADD45GIP1

Background: GADD45GIP1 acts as a negative regulator of G1 to S cell cycle phase progression by inhibiting cyclin-dependent kinases. Inhibitory effects are additive with GADD45 proteins but occurs also in the absence of GADD45 proteins. GADD45GIP1 acts as a repressor of the orphan nuclear receptor NR4A1 by inhibiting AB domain-mediated transcriptional activity. GADD45GIP1 may be involved in the hormone-mediated regulation of NR4A1 transcriptional activity.
Alias Symbols: CKBBP2, CRIF1, MGC4667, MGC4758, PLINP-1, PRG6, Plinp1
Protein Interaction Partner: FBXW11, UBC, LIN28A, EXOSC4, UPF2, TMEM177, MRPL11, MRPL14, TSR1, PTRH2, EIF3C, TAP1, MRPL12, APP, COPS5, HNRNPA1, NFE2L2, ICT1, AR, IKBKG, GADD45G, GADD45B, NR4A1, GADD45A, CSNK2B,
Protein Size: 222

Molecular Weight: 24 kDa

Gene ID: 90480

NCBI Accession: NM_052850, NP_443082

UniProt: Q8TAE8