FGD3 antibody (Middle Region)

Catalog No. ABIN2789126

The Rabbit Polyclonal anti-FGD3 antibody is suitable to detect FGD3 in samples from Human, Mouse, Rat, Horse, Rabbit, Cow and Pig. It has been validated for WB.

Quick Overview for FGD3 antibody (Middle Region) (ABIN2789126)

Target: FGD3 (FYVE, RhoGEF and PH Domain Containing 3 (FGD3))

Reactivity: Human, Mouse, Rat, Horse, Rabbit, Cow, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FGD3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-FGD3 Antibody

Binding Specificity: Middle Region

Purpose: FGD3 Antibody - middle region

Sequence: STSPVEPVVT TEGSSGAAGL EPRKLSSKTR RDKEKQSCKS CGETFNSITK

Predicted Reactivity: Cow: 92%, Horse: 85%, Human: 100%, Mouse: 86%, Pig: 85%, Rabbit: 79%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against FGD3. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP62387-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for FGD3

Target: FGD3 (FYVE, RhoGEF and PH Domain Containing 3 (FGD3))

Alternative Name: FGD3

Background:

Background Information: FGD3 promotes the formation of filopodia. It may activate CDC42, a member of the Ras-like family of Rho- and Rac proteins, by exchanging bound GDP for free GTP. FGD3 plays a role in regulating the actin cytoskeleton and cell shape.

Gene Name: FYVE, RhoGEF and PH domain containing 3

Alternative Symbols: ZFYVE5

Protein Name: FYVE, RhoGEF and PH domain-containing protein 3

Molecular Weight: 70kDa

Gene ID: 89846

NCBI Accession: NP_149077

UniProt: Q5JSP0