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DCTN3 antibody (C-Term)

Dctn3 Reactivity: Human, Rat, Mouse, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio) WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2789148
  • Target See all DCTN3 (Dctn3) Antibodies
    DCTN3 (Dctn3) (Dynactin 3 (p22) (Dctn3))
    Binding Specificity
    • 15
    • 5
    • 3
    • 2
    • 1
    • 1
    C-Term
    Reactivity
    • 20
    • 19
    • 16
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Rat, Mouse, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio)
    Host
    • 31
    • 2
    • 2
    Rabbit
    Clonality
    • 35
    Polyclonal
    Conjugate
    • 11
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This DCTN3 antibody is un-conjugated
    Application
    • 21
    • 13
    • 13
    • 12
    • 5
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB)
    Sequence
    ARLQRLAQIH IQQQDQCVEI TEESKALLEE YNKTTMLLSK QFVQWDELLC
    Predicted Reactivity
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%
    Characteristics
    This is a rabbit polyclonal antibody against DCTN3. It was validated on Western Blot.
    Purification
    Affinity Purified
    Top Product
    Discover our top product Dctn3 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 186 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    DCTN3 (Dctn3) (Dynactin 3 (p22) (Dctn3))
    Alternative Name
    DCTN3 (Dctn3 Products)
    Synonyms
    zgc:92471 antibody, wu:fc38g10 antibody, p24 antibody, NV12799 antibody, DCTN-22 antibody, DCTN22 antibody, dynactin 3 (p22) antibody, dynactin subunit 3 antibody, dynactin 3 antibody, dctn3 antibody, LOC658790 antibody, Dctn3 antibody, DCTN3 antibody
    Background
    This gene encodes the smallest subunit of dynactin, a macromolecular complex consisting of 10 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, cytokinesis, chromosome movement, nuclear positioning, and axonogenesis. This subunit, like most other dynactin subunits, exists only as a part of the dynactin complex. It is primarily an alpha-helical protein with very little coiled coil, and binds directly to the largest subunit (p150) of dynactin. Alternative splicing of this gene generates 2 transcript variants.
    Alias Symbols: DCTN-22, DCTN22, MGC111190
    Protein Interaction Partner: LMNB1, FLNB, FHL2, LEO1, TNKS1BP1, NUP85, CCAR2, ACTR10, DCTN2, ACTR1A, UBC, ACTR1B, DYNLT3, ATXN1, GSK3B, Dctn3, Dctn1, Capza1, PBX2,
    Protein Size: 186
    Molecular Weight
    20 kDa
    Gene ID
    11258
    NCBI Accession
    NM_001248, NP_001239
    UniProt
    O75355
    Pathways
    M Phase
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