RPA2 antibody (N-Term)

Catalog No. ABIN2789160

The Rabbit Polyclonal anti-RPA2 antibody has been validated for WB. It is suitable to detect RPA2 in samples from Human, Mouse, Rat, Dog, Pig, Cow and Guinea Pig.

Quick Overview for RPA2 antibody (N-Term) (ABIN2789160)

Target: RPA2 (Replication Protein A2, 32kDa (RPA2))

Reactivity: Human, Mouse, Rat, Dog, Pig, Cow, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RPA2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-RPA2 Antibody

Binding Specificity: N-Term

Sequence: GSPAPSQAEK KSRARAQHIV PCTISQLLSA TLVDEVFRIG NVEISQVTIV

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 92%, Human: 100%, Mouse: 92%, Pig: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against RPA2. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 270 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for RPA2

Target: RPA2 (Replication Protein A2, 32kDa (RPA2))

Alternative Name: RPA2

Background: RPA2 is required for DNA recombination, repair and replication. The activity of RP-A is mediated by single-stranded DNA binding and protein interactions. Required for the efficient recruitment of the DNA double-strand break repair factor RAD51 to chromatin in response to DNA damage.
Alias Symbols: REPA2, RPA32
Protein Interaction Partner: HUWE1, APITD1, STRA13, FBXO18, UBC, PPP1R10, PPP1CC, POLR2E, POLA1, EXOSC10, PRDX1, NUMA1, NTHL1, NPM1, NONO, NCL, NBN, HNRNPM, PPP1R12A, MYO1E, MYO1C, MYH11, MYH10, MYH9, MYO1F, MTHFD1, MSH3, MSH2, MYO1B, MRE11A, MPG, MOV10, MNAT1, RAB8A, MAP4, CAPRIN1,
Protein Size: 270

Molecular Weight: 30 kDa

Gene ID: 6118

NCBI Accession: NM_015659, NP_056474

UniProt: O76021

Pathways: Telomere Maintenance, DNA Damage Repair, Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA