MRPS11 antibody (Middle Region)

Catalog No. ABIN2789181

The Rabbit Polyclonal anti-MRPS11 antibody is suitable to detect MRPS11 in samples from Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse and Rabbit. It has been validated for WB.

Quick Overview for MRPS11 antibody (Middle Region) (ABIN2789181)

Target: MRPS11 (Mitochondrial Ribosomal Protein S11 (MRPS11))

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MRPS11 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-MRPS11 Antibody

Binding Specificity: Middle Region

Purpose: MRPS11 Antibody - middle region

Sequence: GTEGFRNAKK GTGIAAQTAG IAAAARAKQK GVIHIRVVVK GLGPGRLSAM

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against MRPS11. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP62568-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for MRPS11

Target: MRPS11 (Mitochondrial Ribosomal Protein S11 (MRPS11))

Alternative Name: MRPS11

Background:

Background Information: Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75 % protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that contains a high level of sequence similarity with ribosomal protein S11P family members. A pseudogene corresponding to this gene is found on chromosome 20. Sequence analysis identified two transcript variants that encode different protein isoforms.

Gene Name: Mitochondrial ribosomal protein S11

Alternative Symbols: HCC-2, S11mt, MRP-S11

Protein Name: Mitochondrial fission regulator 1 Ensembl ENSP00000391502

Molecular Weight: 17kDa

Gene ID: 64963

NCBI Accession: NP_001139310

UniProt: E7EP84