OBFC1 antibody (C-Term)

Catalog No. ABIN2789184

The Rabbit Polyclonal anti-OBFC1 antibody (ABIN2789184) specifically detects OBFC1 in WB. The antibody is reactive with Human, Mouse, Rat, Dog, Guinea Pig, Pig, Cow and Horse samples.

Quick Overview for OBFC1 antibody (C-Term) (ABIN2789184)

Target: OBFC1 (Oligonucleotide/oligosaccharide-Binding Fold Containing 1 (OBFC1))

Reactivity: Human, Mouse, Rat, Dog, Guinea Pig, Pig, Cow, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This OBFC1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-OBFC1 Antibody

Binding Specificity: C-Term

Purpose: STN1 Antibody - C-terminal region

Sequence: DKDLHRKIHR IIQQDCQKPN HMEKGCHFLH ILACARLSIR PGLSEAVLQQ

Predicted Reactivity: Cow: 79%, Dog: 86%, Guinea Pig: 79%, Horse: 93%, Human: 100%, Mouse: 86%, Pig: 86%, Rat: 79%

Characteristics: This is a rabbit polyclonal antibody against OBFC1. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP62578-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for OBFC1

Target: OBFC1 (Oligonucleotide/oligosaccharide-Binding Fold Containing 1 (OBFC1))

Alternative Name: STN1

Background:

Targeted Subunit: STN1

Background Information: OBFC1 and C17ORF68 (MIM 613129) are subunits of an alpha accessory factor (AAF) that stimulates the activity of DNA polymerase-alpha-primase (see MIM 176636), the enzyme that initiates DNA replication (Casteel et al., 2009 [PubMed 19119139]). OBFC1 also appears to function in a telomere-associated complex with C17ORF68 and TEN1 (C17ORF106, MIM 613130) (Miyake et al., 2009 [PubMed 19854130]).[supplied by OMIM, Nov 2009]

Gene Name: STN1, CST complex subunit

Alternative Symbols: AAF44, OBFC1, AAF-44, RPA-32, bA541N10.2

Protein Name: CST complex subunit STN1

Molecular Weight: 40kDa

Gene ID: 79991

NCBI Accession: NP_079204

UniProt: Q9H668