MRPL46 antibody (C-Term)

Catalog No. ABIN2789278

Product Details anti-MRPL46 Antibody

Target: MRPL46 (Mitochondrial Ribosomal Protein L46 (MRPL46))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Guinea Pig, Cow, Dog, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MRPL46 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: KVFFFKALLL TGDFSQAGNK GHHVWVTKDE LGDYLKPKYL AQVRRFVSDL

Predicted Reactivity: Cow: 92%, Dog: 92%, Guinea Pig: 100%, Horse: 92%, Human: 100%, Mouse: 85%, Rabbit: 77%, Rat: 92%

Characteristics: This is a rabbit polyclonal antibody against MRPL46. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 279 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for MRPL46

Target: MRPL46 (Mitochondrial Ribosomal Protein L46 (MRPL46))

Alternative Name: MRPL46 (MRPL46 Products)

Background: Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75 % protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein.
Alias Symbols: C15orf4, LIECG2, MGC22762, P2ECSL
Protein Interaction Partner: NEDD1, NPM1, C1QBP, EIF3F, EIF3A, ATP6V0A1, MARCKSL1, MRPL4, MRPL3, SLC25A13, FUBP1, UBC, ICT1,
Protein Size: 279

Molecular Weight: 31 kDa

Gene ID: 26589

NCBI Accession: NM_022163, NP_071446

UniProt: Q9H2W6