SRI antibody (C-Term)

Catalog No. ABIN2789324

Product Details anti-SRI Antibody

Target: SRI (Sorcin (SRI))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Horse, Dog, Cow, Rabbit, Sheep, Guinea Pig, Zebrafish (Danio rerio), Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SRI antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: QAVNSIAKRY STNGKITFDD YIACCVKLRA LTDSFRRRDT AQQGVVNFPY

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 86%, Pig: 100%, Rabbit: 93%, Rat: 92%, Sheep: 100%, Zebrafish: 85%

Characteristics: This is a rabbit polyclonal antibody against SRI. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 198 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for SRI

Target: SRI (Sorcin (SRI))

Alternative Name: SRI (SRI Products)

Background: SRI is a calcium-binding protein that modulates excitation-contraction coupling in the heart. It contributes to calcium homeostasis in the heart sarcoplasmic reticulum. It modulates the activity of RYR2 calcium channels.
Alias Symbols: FLJ26259, SCN, CP22
Protein Interaction Partner: PRR13, CALCOCO2, TCF12, PDE4C, GCA, STAT3, SRI, HAUS2, UBC, SRPK2, VCAM1, SMAD2, ITGA4, FN1, SNCA, SHBG, NRAS, RUVBL1, ANXA11, PSEN2, ANXA7, RYR2, CACNA1S, CACNA1C, ALG2,
Protein Size: 198

Molecular Weight: 22 kDa

Gene ID: 6717

NCBI Accession: NM_003130, NP_003121

UniProt: P30626

Pathways: Transition Metal Ion Homeostasis, Maintenance of Protein Location, Negative Regulation of Transporter Activity