AVPR1B antibody (C-Term)

Catalog No. ABIN2789328

The Rabbit Polyclonal anti-AVPR1B antibody is suitable to detect AVPR1B in samples from Human, Rat, Mouse, Dog, Cow, Horse, Rabbit, Guinea Pig and Sheep. It has been validated for WB.

Quick Overview for AVPR1B antibody (C-Term) (ABIN2789328)

Target: AVPR1B (Arginine Vasopressin Receptor 1B (AVPR1B))

Reactivity: Human, Rat, Mouse, Dog, Cow, Horse, Rabbit, Guinea Pig, Sheep

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AVPR1B antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-AVPR1B Antibody

Binding Specificity: C-Term

Sequence: TISRAKIRTV KMTFVIVLAY IACWAPFFSV QMWSVWDKNA PDEDSTNVAF

Predicted Reactivity: Cow: 93%, Dog: 100%, Guinea Pig: 93%, Horse: 75%, Human: 100%, Mouse: 86%, Rabbit: 86%, Rat: 86%, Sheep: 93%

Characteristics: This is a rabbit polyclonal antibody against AVPR1B. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 424 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for AVPR1B

Target: AVPR1B (Arginine Vasopressin Receptor 1B (AVPR1B))

Alternative Name: AVPR1B

Background: The protein encoded by this gene acts as receptor for arginine vasopressin. This receptor belongs to the subfamily of G-protein coupled receptors which includes AVPR1A, V2R and OXT receptors. Its activity is mediated by G proteins which stimulate a phosphatidylinositol-calcium second messenger system. The receptor is primarily located in the anterior pituitary, where it stimulates ACTH release. It is expressed at high levels in ACTH-secreting pituitary adenomas as well as in bronchial carcinoids responsible for the ectopic ACTH syndrome. A spliced antisense transcript of this gene has been reported but its function is not known.
Alias Symbols: AVPR3
Protein Interaction Partner: GRK5, AVP, PRKCA,
Protein Size: 424

Molecular Weight: 47 kDa

Gene ID: 553

NCBI Accession: NM_000707, NP_000698

UniProt: P47901

Pathways: Regulation of Systemic Arterial Blood Pressure by Hormones