SHBG antibody (C-Term)

Catalog No. ABIN2789331

This Rabbit Polyclonal antibody specifically detects SHBG in WB. It exhibits reactivity toward Human and Rabbit.

Quick Overview for SHBG antibody (C-Term) (ABIN2789331)

Target: SHBG (Sex Hormone Binding Globulin (SHBG))

Reactivity: Human, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SHBG antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-SHBG Antibody

Binding Specificity: C-Term

Purpose: SHBG Antibody - C-terminal region

Sequence: RGEDSSTSFC LNGLWAQGQR LDVDQALNRS HEIWTHSCPQ SPGNGTDASH

Predicted Reactivity: Human: 100%, Rabbit: 86%

Characteristics: This is a rabbit polyclonal antibody against SHBG. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of SHBG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP63002-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for SHBG

Target: SHBG (Sex Hormone Binding Globulin (SHBG))

Alternative Name: SHBG

Background:

Background Information: This gene encodes a steroid binding protein that was first described as a plasma protein secreted by the liver but is now thought to participate in the regulation of steroid responses. The encoded protein binds each steroid molecule as a dimer formed from identical or nearly identical monomers. The use of alternate promoters and alternatively spliced transcripts have been described. Multiple transcript variants encoding different isoforms have been found for this gene.

Alternative Symbols: ABP, SBP, TEBG

Protein Name: Sex hormone-binding globulin Ensembl ENSP00000393426

Molecular Weight: 31kDa

Gene ID: 6462

NCBI Accession: NP_001139753

UniProt: E9PGW1

Pathways: Hormone Transport