SHBG antibody (N-Term)

Catalog No. ABIN2789332

This Rabbit Polyclonal antibody specifically detects SHBG in WB. It exhibits reactivity toward Human, Rat, Mouse, Cow, Rabbit, Dog and Horse.

Quick Overview for SHBG antibody (N-Term) (ABIN2789332)

Target: SHBG (Sex Hormone Binding Globulin (SHBG))

Reactivity: Human, Rat, Mouse, Cow, Rabbit, Dog, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SHBG antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-SHBG Antibody

Binding Specificity: N-Term

Sequence: FDLTKITKTS SSFEVRTWDP EGVIFYGDTN PKDDWFMLGL RDGRPEIQLH

Predicted Reactivity: Cow: 93%, Dog: 93%, Horse: 86%, Human: 100%, Mouse: 86%, Rabbit: 93%, Rat: 86%

Characteristics: This is a rabbit polyclonal antibody against SHBG. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of human SHBG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for SHBG

Target: SHBG (Sex Hormone Binding Globulin (SHBG))

Alternative Name: SHBG

Background: This gene encodes a steroid binding protein that was first described as a plasma protein secreted by the liver but is now thought to participate in the regulation of steroid responses. The encoded protein transports androgens and estrogens in the blood, binding each steroid molecule as a dimer formed from identical or nearly identical monomers. Polymorphisms in this gene have been associated with polycystic ovary syndrome and type 2 diabetes mellitus. Alternative splicing results in multiple transcript variants.
Alias Symbols: ABP, SBP, TEBG
Protein Size: 229

Molecular Weight: 25 kDa

Gene ID: 6462

NCBI Accession: NM_001040, NP_001031

UniProt: P04278

Pathways: Hormone Transport