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MCC antibody (C-Term)

MCC Reactivity: Human, Mouse, Rat, Guinea Pig, Horse, Dog WB, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2789347
  • Target See all MCC Antibodies
    MCC (Mutated in Colorectal Cancers (MCC))
    Binding Specificity
    • 15
    • 7
    • 7
    • 6
    • 6
    • 4
    • 3
    • 2
    • 1
    C-Term
    Reactivity
    Human, Mouse, Rat, Guinea Pig, Horse, Dog
    Host
    • 40
    • 3
    Rabbit
    Clonality
    • 42
    • 1
    Polyclonal
    Conjugate
    • 15
    • 4
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MCC antibody is un-conjugated
    Application
    • 38
    • 22
    • 13
    • 13
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Sequence
    SSTSSGSKDK PGKECADAAS PALSLAELRT TCSENELAAE FTNAIRREKK
    Predicted Reactivity
    Dog: 93%, Guinea Pig: 100%, Horse: 86%, Human: 100%, Mouse: 79%, Rat: 93%
    Characteristics
    This is a rabbit polyclonal antibody against MCC. It was validated on Western Blot.
    Purification
    Affinity Purified
    Top Product
    Discover our top product MCC Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 829 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    MCC (Mutated in Colorectal Cancers (MCC))
    Alternative Name
    MCC (MCC Products)
    Synonyms
    MCC antibody, mcc1 antibody, MCC1 antibody, D18Ertd451e antibody, E330037C19 antibody, RGD1561988 antibody, mutated in colorectal cancers antibody, MCC antibody, mcc antibody, Mcc antibody
    Background
    This gene is a candidate colorectal tumor suppressor gene that is thought to negatively regulate cell cycle progression. The orthologous gene in the mouse expresses a phosphoprotein associated with the plasma membrane and membrane organelles, and overexpression of the mouse protein inhibits entry into S phase. Multiple transcript variants encoding different isoforms have been found for this gene.
    Alias Symbols: DKFZp762O1615, FLJ38893, FLJ46755, MCC1
    Protein Interaction Partner: CSNK1E, ERBB2IP, CBX5, GTF2E2, APP, DYNC1I1, NEK2, NFKBIB, STRIP1, VPS35, STRN3, STRN4, SNRNP200, PDCD10, PAICS, PSME3, CCNA1, EIF3A, STK24, EZR, VHL, VDAC1, VCP, TPM3, TARS, STRN, PSMD2, PPP2R1A, PFKP, PFAS, MYH10, MTHFD1, MARS, LTA4H, KRT18, IARS, HPRT1
    Protein Size: 829
    Molecular Weight
    91 kDa
    Gene ID
    4163
    NCBI Accession
    NM_002387, NP_002378
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