PPP2CA antibody (N-Term)

Catalog No. ABIN2789352

This Rabbit Polyclonal antibody specifically detects PPP2CA in WB. It exhibits reactivity toward Human, Mouse, Rat, Cow, Rabbit, Zebrafish (Danio rerio), Dog, Guinea Pig and Horse.

Quick Overview for PPP2CA antibody (N-Term) (ABIN2789352)

Target: PPP2CA (Protein Phosphatase 2, Catalytic Subunit, alpha Isozyme (PPP2CA))

Reactivity: Human, Mouse, Rat, Cow, Rabbit, Zebrafish (Danio rerio), Dog, Guinea Pig, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PPP2CA antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PPP2CA Antibody

Binding Specificity: N-Term

Sequence: LSESQVKSLC EKAKEILTKE SNVQEVRCPV TVCGDVHGQF HDLMELFRIG

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against PPP2CA. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 309 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PPP2CA

Target: PPP2CA (Protein Phosphatase 2, Catalytic Subunit, alpha Isozyme (PPP2CA))

Alternative Name: PPP2CA

Background: This gene encodes the phosphatase 2A catalytic subunit. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. This gene encodes an alpha isoform of the catalytic subunit.
Alias Symbols: PP2Ac, PP2CA, PP2Calpha, RP-C
Protein Interaction Partner: ZFP36, UBC, MID1, VAC14, SETBP1, PPP2R1A, SUMO2, ESPL1, HTT, VCP, ZNF346, NEDD8, SUMO1, RPA3, RPA2, RPA1, HNRNPH1, NIF3L1, TNPO3, AHCYL1, ARPC4, SSB, PFDN1, NRD1, TNPO1, IGBP1, XRN1, TRIP13, BAG3, STK26, CHEK2, STK25, POLA1, NPM1, STK24, CTDP1, RAF1, ID1,
Protein Size: 309

Molecular Weight: 34 kDa

Gene ID: 5515

NCBI Accession: NM_002715, NP_002706

UniProt: P67775

Pathways: PI3K-Akt Signaling, Mitotic G1-G1/S Phases, Hepatitis C, Toll-Like Receptors Cascades