BMP4 antibody (C-Term)

Catalog No. ABIN2789354

Cited in 1 publication. The Rabbit Polyclonal anti-BMP4 antibody (ABIN2789354) specifically detects BMP4 in WB. The antibody is reactive with Human, Rat, Mouse, Rabbit, Pig, Cow, Dog, Goat, Sheep, Guinea Pig and Horse samples.

Quick Overview for BMP4 antibody (C-Term) (ABIN2789354)

Target: BMP4 (Bone Morphogenetic Protein 4 (BMP4))

Reactivity: Human, Rat, Mouse, Rabbit, Pig, Cow, Dog, Goat, Sheep, Guinea Pig, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BMP4 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-BMP4 Antibody

Binding Specificity: C-Term

Purpose: BMP4 Antibody - C-terminal region

Sequence: NWAQLRPLLV TFGHDGRGHA LTRRRRAKRS PKHHSQRARK KNKNCRRHSL

Predicted Reactivity: Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 92%, Horse: 100%, Human: 100%, Mouse: 92%, Pig: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%

Characteristics: This is a rabbit polyclonal antibody against BMP4. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP63062-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

References for anti-BMP4 antibody (ABIN2789354)

Ganti, Hunt, Parapuram, Hunt: "Vitreous modulation of gene expression in low-passage human retinal pigment epithelial cells." in: Investigative ophthalmology & visual science, Vol. 48, Issue 4, pp. 1853-63, (2007) (PubMed).

Target Details for BMP4

Target: BMP4 (Bone Morphogenetic Protein 4 (BMP4))

Alternative Name: BMP4

Background:

Background Information: The protein encoded by this gene is a member of the bone morphogenetic protein family which is part of the transforming growth factor-beta superfamily. The superfamily includes large families of growth and differentiation factors. Bone morphogenetic proteins were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. This particular family member plays an important role in the onset of endochondral bone formation in humans, and a reduction in expression has been associated with a variety of bone diseases, including the heritable disorder Fibrodysplasia Ossificans Progressiva. Alternative splicing in the 5' untranslated region of this gene has been described and three variants are described, all encoding an identical protein.

Gene Name: Bone morphogenetic protein 4

Alternative Symbols: ZYME, BMP2B, OFC11, BMP2B1, MCOPS6

Protein Name: Bone morphogenetic protein 4

Molecular Weight: 40 kDa

Gene ID: 652

NCBI Accession: NP_001193

UniProt: P12644

Pathways: Steroid Hormone Mediated Signaling Pathway, Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development