STAM antibody (N-Term)

Catalog No. ABIN2789368

This Rabbit Polyclonal antibody specifically detects STAM in WB. It exhibits reactivity toward Human, Mouse, Rat, Cow, Dog, Rabbit, Guinea Pig, Horse and Zebrafish (Danio rerio).

Quick Overview for STAM antibody (N-Term) (ABIN2789368)

Target: STAM (Signal Transducing Adaptor Molecule (SH3 Domain and ITAM Motif) 1 (STAM))

Reactivity: Human, Mouse, Rat, Cow, Dog, Rabbit, Guinea Pig, Horse, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This STAM antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-STAM Antibody

Binding Specificity: N-Term

Sequence: EQAKASPALV AKDPGTVANK KEEEDLAKAI ELSLKEQRQQ STTLSTLYPS

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 82%

Characteristics: This is a rabbit polyclonal antibody against STAM. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 540 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for STAM

Target: STAM (Signal Transducing Adaptor Molecule (SH3 Domain and ITAM Motif) 1 (STAM))

Alternative Name: STAM

Background: This gene encodes a member of the signal-transducing adaptor molecule family. These proteins mediate downstream signaling of cytokine receptors and also play a role in ER to Golgi trafficking by interacting with the coat protein II complex. The encoded protein also associates with hepatocyte growth factor-regulated substrate to form the endosomal sorting complex required for transport-0 (ESCRT-0), which sorts ubiquitinated membrane proteins to the ESCRT-1 complex for lysosomal degradation. Alternatively spliced transcript variants have been observed for this gene.
Alias Symbols: DKFZp686J2352, STAM1, STAM-1
Protein Interaction Partner: DTX3L, HGS, UBC, CLTC, Chmp3, UBE4B, STAMBP, YWHAB, SNTA1, Mbp, MED28, PPP1CA, PPP1CC, UBQLN4, UBQLN2, PRDX5, STMN2, CPLX1, AHCYL1, SSSCA1, STUB1, USP34, ZRANB2, ZPR1, PIR, TPM2, SULT1A1, S100A11, PPM1G, IGBP1, SERPINH1, TBCK, UNK, THADA, TRIM54, USP15, R
Protein Size: 540

Molecular Weight: 59 kDa

Gene ID: 8027

NCBI Accession: NM_003473, NP_003464

UniProt: Q92783

Pathways: EGFR Signaling Pathway, EGFR Downregulation