CD1d antibody (C-Term)

Catalog No. ABIN2789370

The Rabbit Polyclonal anti-CD1d antibody (ABIN2789370) specifically detects CD1d in WB. The antibody is reactive with Human samples.

Quick Overview for CD1d antibody (C-Term) (ABIN2789370)

Target: CD1d (CD1D) (CD1d Molecule (CD1D))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CD1d antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CD1d Antibody

Binding Specificity: C-Term

Purpose: CD1D Antibody - C-terminal region

Sequence: LEGQDIVLYW GGSYTSMGLI ALAVLACLLF LLIVGFTSRF KRQTSYQGVL

Predicted Reactivity: Human: 100%

Characteristics: This is a rabbit polyclonal antibody against CD1D. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP63099-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for CD1d

Target: CD1d (CD1D) (CD1d Molecule (CD1D))

Alternative Name: CD1D

Background:

Background Information: This gene encodes a divergent member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes to late endosomes and lysosomes via a tyrosine-based motif in the cytoplasmic tail.

Gene Name: CD1d molecule

Alternative Symbols: R3, CD1A, R3G1

Protein Name: Antigen-presenting glycoprotein CD1d

Molecular Weight: 38kDa

Gene ID: 912

NCBI Accession: NP_001757

UniProt: P15813

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process