SCARB1 antibody (N-Term)

Catalog No. ABIN2789394

This anti-SCARB1 antibody is a Rabbit Polyclonal antibody detecting SCARB1 in WB and IHC. Suitable for Human, Rat, Mouse, Cow, Dog, Guinea Pig and Rabbit. This Primary Antibody has been cited in 1 publication.

Quick Overview for SCARB1 antibody (N-Term) (ABIN2789394)

Target: SCARB1 (Scavenger Receptor Class B, Member 1 (SCARB1))

Reactivity: Human, Rat, Mouse, Cow, Dog, Guinea Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SCARB1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-SCARB1 Antibody

Binding Specificity: N-Term

Sequence: LEYRTFQFQP SKSHGSESDY IVMPNILVLG AAVMMENKPM TLKLIMTLAF

Predicted Reactivity: Cow: 79%, Dog: 86%, Guinea Pig: 79%, Human: 100%, Mouse: 86%, Rabbit: 86%, Rat: 79%

Characteristics: This is a rabbit polyclonal antibody against SCARB1. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 506 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-SCARB1 antibody (ABIN2789394)

Fu, Mukhamedova, Ip, DSouza, Henley, DiTommaso, Kesani, Ditiatkovski, Jones, Lane, Jennings, Smyth, Kile, Sviridov: "ABCA12 regulates ABCA1-dependent cholesterol efflux from macrophages and the development of atherosclerosis." in: Cell metabolism, Vol. 18, Issue 2, pp. 225-38, (2013) (PubMed).

Target Details for SCARB1

Target: SCARB1 (Scavenger Receptor Class B, Member 1 (SCARB1))

Alternative Name: SCARB1

Background: The protein encoded by this gene is a plasma membrane receptor for high density lipoprotein cholesterol (HDL). The encoded protein mediates cholesterol transfer to and from HDL. In addition, this protein is a receptor for hepatitis C virus glycoprotein E2. Two transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: CD36L1, CLA-1, CLA1, MGC138242, SR-BI, SRB1, HDLQTL6
Protein Interaction Partner: KRTAP10-9, KRTAP5-9, UBC, FBXO6, CAND1, CUL1, APOA2, APOA1, PDZK1, PEX5, APOE,
Protein Size: 506

Molecular Weight: 56 kDa

Gene ID: 949

NCBI Accession: NM_001082959, NP_001076428

UniProt: F8W8N0

Pathways: Cellular Response to Molecule of Bacterial Origin, Hepatitis C, Lipid Metabolism, SARS-CoV-2 Protein Interactome