MUTED antibody (C-Term)

Catalog No. ABIN2789438

This anti-MUTED antibody is a Rabbit Polyclonal antibody detecting MUTED in WB. Suitable for Human, Mouse, Cow, Horse, Rat, Dog, Rabbit and Guinea Pig.

Quick Overview for MUTED antibody (C-Term) (ABIN2789438)

Target: MUTED (Muted Homolog (MUTED))

Reactivity: Human, Mouse, Cow, Horse, Rat, Dog, Rabbit, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MUTED antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-MUTED Antibody

Binding Specificity: C-Term

Sequence: QQREQERKKI HSDHLVASEK QHMLQWDNFM KEQPNKRAEV DEEHRKAMER

Predicted Reactivity: Cow: 79%, Dog: 79%, Guinea Pig: 77%, Horse: 86%, Human: 100%, Mouse: 85%, Rabbit: 86%, Rat: 79%

Characteristics: This is a rabbit polyclonal antibody against MUTED. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 187 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for MUTED

Target: MUTED (Muted Homolog (MUTED))

Alternative Name: MUTED

Background: This gene encodes a component of BLOC-1 (biogenesis of lysosome-related organelles complex 1). Components of this complex are involved in the biogenesis of organelles such as melanosomes and platelet-dense granules. A mouse model for Hermansky-Pudlak Syndrome is mutated in the murine version of this gene. Alternative splicing results in multiple transcript variants. Read-through transcription exists between this gene and the upstream EEF1E1 (eukaryotic translation elongation factor 1 epsilon 1) gene, as well as with the downstream TXNDC5 (thioredoxin domain containing 5) gene.
Alias Symbols: DKFZp686E2287, MU, MUTED
Protein Interaction Partner: HUWE1, TSNAX, UBC, APP, DCUN1D1, SQSTM1, YOD1, BLOC1S2, BLOC1S4, DTNBP1, SNAPIN, BLOC1S1, BLOC1S6, BLOC1S3,
Protein Size: 187

Molecular Weight: 21 kDa

Gene ID: 63915

NCBI Accession: NM_201280, NP_958437

UniProt: Q8TDH9