MUTED antibody (C-Term)

Catalog No. ABIN2789439

The Rabbit Polyclonal anti-MUTED antibody has been validated for WB. It is suitable to detect MUTED in samples from Human, Mouse, Cow, Horse, Rat, Dog, Rabbit and Pig.

Quick Overview for MUTED antibody (C-Term) (ABIN2789439)

Target: MUTED (Muted Homolog (MUTED))

Reactivity: Human, Mouse, Cow, Horse, Rat, Dog, Rabbit, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MUTED antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-MUTED Antibody

Binding Specificity: C-Term

Sequence: LSQVLQRLQA ANDSVCRLQQ REQERKKIHS DHLVASEKQH MLQWDNFMKE

Predicted Reactivity: Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 92%, Rabbit: 100%, Rat: 92%

Characteristics: This is a rabbit polyclonal antibody against MUTED. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of MUTED

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 187 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for MUTED

Target: MUTED (Muted Homolog (MUTED))

Alternative Name: MUTED

Background: This gene encodes a component of BLOC-1 (biogenesis of lysosome-related organelles complex 1). Components of this complex are involved in the biogenesis of organelles such as melanosomes and platelet-dense granules. A mouse model for Hermansky-Pudlak Syndrome is mutated in the murine version of this gene. Alternative splicing results in multiple transcript variants. Read-through transcription exists between this gene and the upstream EEF1E1 (eukaryotic translation elongation factor 1 epsilon 1) gene, as well as with the downstream TXNDC5 (thioredoxin domain containing 5) gene.
Alias Symbols: DKFZp686E2287, MU, MUTED
Protein Interaction Partner: HUWE1, TSNAX, UBC, APP, DCUN1D1, SQSTM1, YOD1, BLOC1S2, BLOC1S4, DTNBP1, SNAPIN, BLOC1S1, BLOC1S6, BLOC1S3,
Protein Size: 187

Molecular Weight: 21 kDa

Gene ID: 63915

NCBI Accession: NM_201280, NP_958437

UniProt: Q8TDH9