BCAR1 antibody (C-Term)

Catalog No. ABIN2789463

The Rabbit Polyclonal anti-BCAR1 antibody has been validated for WB. It is suitable to detect BCAR1 in samples from Human, Mouse, Rat, Dog, Cow, Guinea Pig, Horse, Rabbit and Zebrafish (Danio rerio).

Quick Overview for BCAR1 antibody (C-Term) (ABIN2789463)

Target: BCAR1 (Breast Cancer Anti-Estrogen Resistance 1 (BCAR1))

Reactivity: Human, Mouse, Rat, Dog, Cow, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BCAR1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-BCAR1 Antibody

Binding Specificity: C-Term

Sequence: YVHLQGKEEF EKTQKELLEK GSITRQGKSQ LELQQLKQFE RLEQEVSRPI

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%

Characteristics: This is a rabbit polyclonal antibody against BCAR1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human BCAR1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 660 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for BCAR1

Target: BCAR1 (Breast Cancer Anti-Estrogen Resistance 1 (BCAR1))

Alternative Name: BCAR1

Background: BCAR1, or CAS, is an Src family kinase substrate involved in various cellular events, including migration, survival, transformation, and invasion.
Alias Symbols: CAS, CAS1, CASS1, CRKAS, FLJ12176, FLJ45059, P130Cas
Protein Interaction Partner: KIF13A, ARMCX3, GMPR2, EPN1, HYOU1, TSEN34, YWHAE, UBC, MMP14, NCK1, CRKL, CRK, BMX, PTK2, PTK2B, ESR1, CBL, NPHP1, ITGAV, SRC, RAN, CDC42, TNK2, SH3KBP1, CD2AP, UHRF2, AJUBA, VPS11, ARHGAP32, NEDD9, SRCIN1, EFS, FXYD6, PPP1R15A, PPAP2B, SH2D3C, SH2D3A, T
Protein Size: 660

Molecular Weight: 72 kDa

Gene ID: 9564

NCBI Accession: NM_001170721, NP_001164192

UniProt: B3KWE2

Pathways: EGFR Signaling Pathway, Neurotrophin Signaling Pathway, CXCR4-mediated Signaling Events, Platelet-derived growth Factor Receptor Signaling